Oncotarget Proves Cigarettes Cause Multiple Human Gum Tissue Issues

Oncotarget is a free-access multidisciplinary traditional journal. Papers are published online every week. If there is a special demand, issues or papers can be printed as well. Oncotarget’s mission is to make scientific results rapidly and widely available. They seek to maximize the impact of research through insightful reviewing techniques and wish to share exceptional discoveries with the public. Oncotarget seeks to have the greatest impact as possible while allowing discoveries to be shared with the world. Oncotarget seeks to link different fields of biomedical science and ultimately lower the borders between different specialties. As a way of fighting disease, Oncotarget wishes to promote applications of basic and clinical science. Some of the most prominent scientists lead Oncotarget and help many researchers in contributing to the progress of science. Visit his profile on Google Scholar.

A recent study published by Oncotarget shows that cigarettes are a significant tobacco product consumption which could pose an oral health issue. Details of this study show that in gingival epithelium increases with cigarette smoking as well as DNA damage to human gum tissue which is irreversible and leads to irreversible growth arrest of gum tissue. This study also focuses on e-cigarretes which cause increased oxidative/carbonyl and inflammatory responses, and DNA damage as well as histone deacetylase 2 (HDAC2) reduction through mechanisms in gingival epithelium. A greater response is elicited by flavored e-cigs.

The abstract: E-cigarettes and flavorings induce inflammatory and pro-senescence responses in oral epithelial cells and periodontal fibroblasts are the first of its kind to prove the negative effects to human gum tissue. This study and other studies by Oncotarget are directed to the ultimate goal of one day people being able to live life without disease.

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